Start working on removing those .la files en masse.

chromeos/config/make.conf.amd64-host

Index: chromeos/config/make.conf.amd64-host
diff --git a/chromeos/config/make.conf.amd64-host b/chromeos/config/make.conf.amd64-host
index 75f300f123cfc524bef27b5d13967fd42e332e37..a42da985e6decc433fb2aa7b780558e5890436a3 100644
--- a/chromeos/config/make.conf.amd64-host
+++ b/chromeos/config/make.conf.amd64-host
@@ -28,4 +28,23 @@ USE="${USE} -cups hardened cros_host multilib pic pie"
 GENTOO_MIRRORS="http://commondatastorage.googleapis.com/chromeos-mirror/gentoo"
 GENTOO_MIRRORS="$GENTOO_MIRRORS http://commondatastorage.googleapis.com/chromeos-localmirror"
 
+
+# avoid removing libltdl.la as it is required by some macro files
+INSTALL_MASK="
+/usr/lib/lib[0-9]*.la
+/usr/lib/lib[a-k]*.la
+/usr/lib/lib[m-z]*.la
+/usr/lib/libl[0-9]*.la
+/usr/lib/libl[a-s]*.la
+/usr/lib/libl[u-z]*.la
+/usr/lib/liblt[0-9]*.la
+/usr/lib/liblt[a-c]*.la
+/usr/lib/liblt[e-z]*.la
+/usr/lib/libltd[0-9]*.la
+/usr/lib/libltd[a-k]*.la
+/usr/lib/libltd[m-z]*.la
+/usr/lib/libltdl[0-9]*.la
+/usr/lib/libltdl[a-z]*.la
+"
+
 source make.conf.host_setup